Cyclo(Tyr-Pro)

Catalogue number C104021
Chemical nameCyclo(Tyr-Pro)
CAS Number5654-84-2
Synonyms
Molecular WeightC14H16N2O3
Formula260.3
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Antiviral, antibiotic and antitumour.


The effect of the cyclic dipeptides on the gastrointestinal epithelium was assessed by changes in alkaline phosphatase expression of HT-29 cells. Cyclo(Pro-Trp) and cyclo(Phe-Pro) show broad spectrum antibacterial properties and cyclo(Trp-Pro) and cyclo(Trp-Trp) show broad spectrum antifungal properties. The maturation of the gastrointestinal cells was enhanced by cyclo(Phe-Pro), cyclo(Tyr-Pro), cyclo(Trp-Trp) and cyclo(Trp-Pro). The activity of cyclic dipeptides thus indicates potential application of these compounds as pharmacological agents.

References1. Pharmazie., 1999, 54(10), 772-775.
2. IJSEM, 2004, 54(4), 1177-1184.
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Cyclo(Tyr-Pro)
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