Catalpol

Catalogue number C107890
Chemical nameCatalpol
CAS Number2415-24-9
Synonyms(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside Catalpinoside
Molecular WeightC15H22O10
Formula362.3
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

It primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.


Treatment of PC12 cells with catalpol can block H2O2-induced apoptosis by the regulation of Bcl-2 family members, as well as suppression of cytochrome c release and caspase cascade activation.
Catalpol exerts the most significant cytoprotective effect on astrocytes by suppressing the production of free radicals and elevating antioxidant capacity.
Enzyme inhibitor, antihistaminic.

References1. J.O.C., 1961, 26, 3090-3094.
2. J.O.C., 1966, 31, 500-506.
3. Toxicon, 2004, 43(1), 53–59.
4. International Journal of Developmental Neuroscience, 2008, 26(3-4), 309-317.
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Catalpol
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
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