Calycosin-7-O-beta-D-glucoside

Catalogue number C108557
Chemical nameCalycosin-7-O-beta-D-glucoside
CAS Number20633-67-4
Synonyms3-(3-Hydroxy-4-methoxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-
Molecular WeightC22H22O10
Formula446.4
Purity98%
Physical DescriptionYellow powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Calycosin-7-O-beta-D-glucoside showed more scavenging activity to DPPH radicals than formononetin in the cell-free system.


Calycosin 7-O-β-D-glucopyranoside possesses multiple biological and pharmacological activities such as an alleviating effect on osteoarthritis, a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity, and antimicrobial and superoxide anion scavenging activitie. Additionally, this compound can also efficaciously increase the fluidity of brain cell membrane in ischemia-reperfusion rats. Calycosin 7-O-β-D-glucoside is anticipated to be a promising anti-HIV agent.

References1. Journal of Chromatography B, 2008, 865(1-2), 99-105.
2. Biomedical Chromatography, 2008, 22(2), 157-163.
3. Magnetic Resonance in Chemistry, 2008, 46(1), 103-106.
4. BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2005, 18, 297-301.
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Calycosin-7-O-beta-D-glucoside
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