CDPPB

Catalogue number C213970
Chemical nameCDPPB
CAS Number781652-57-1
Synonyms3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
Molecular WeightC23H16N4O
Formula364.4
Purity98%
Physical DescriptionWhite Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsCDPPB is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that CDPPB suppresses the increase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
ReferencesChen, T. et al.: Neurochem. Res., 37, 983 (2012); Rodriguez, A. et al.: Bioorg. Med. Chem. Lett., 22, 7388 (2012); Gregory, K. et al.: Mol. Pharmacol., 82, 860 (2012)
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CDPPB
Price(USD)
SizePrice(USD)Discount
5mg$90.0010% OFF
25mg$300.0010% OFF
10mg$130.0010% OFF
50mg$575.0010% OFF
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