CCT036477

Catalogue number C213956
Chemical nameCCT036477
CAS Number305372-78-5
Synonymsα-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine;
Molecular WeightC21H18ClN3
Formula347.84
Purity98%
Physical DescriptionOff-White to Pale Beige Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsCCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
ReferencesEwan, K. et al.: Cancer Res., 14, 5963 (2010);
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CCT036477
Price(USD)
SizePrice(USD)Discount
25mg$140.0010% OFF
250mg$1120.0010% OFF
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