| Catalogue number | C212939 |
| Chemical name | C646 |
| CAS Number | 328968-36-1 |
| Synonyms | 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid; C 646 |
| Molecular Weight | C24H18N3O6 |
| Formula | 445.42 |
| Purity | 98% |
| Physical Description | Dark Orange Solid |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | C646 is an inhibitor for histone acetyltransferase p300 and may be a potential candidate for treating AML1-ETO (AE) positive acute myeloid leukemia (AML). It is shown that C646 inhibited cellular proliferation, reduced colony formation, evoked partial cell cycle arrest in the G1 phase, and induced apoptosis in AE-positive AML cell lines and primary blasts isolated from leukemic mice and AML patients. |
| References | Gao, X., et al.: Zhang, X., et al.: PLoS One, 8, e55481 (2013); Zhonghua Shiyan Waike Zazhi, 30, 1177 (2013); Bowers, E.M., et al.: Chem. Biol., 17, 471 (2010) |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 1mg | $45.00 | 10% OFF |
| 10mg | $225.00 | 10% OFF |
| 50mg | $750.00 | 10% OFF |
| 5mg | $125.00 | 10% OFF |
| 25mg | $450.00 | 10% OFF |
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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