Bromoconduritol (Mixture of Isomers)

Catalogue number C209961
Chemical nameBromoconduritol (Mixture of Isomers)
CAS Number42014-74-4
Synonyms6-Bromo-3,4,5-trihydroxy Cyclohex-1-ene; 6-Bromo-4-cyclohexene-1,2,3-triol;
Molecular WeightC6H8O3Br
Formula209.04
Purity98%
Physical DescriptionWhite to Off-White Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsBromoconduritol selectively inhibits mammalian alpha-glucosidase 2 (Glc2/Glc1 glucosidase in the glycoprotein processing pathway), yeast alpha-glucosidase, and some beta-glucosidases. It does not inhibit mammalian alpha-glucosidase 1 (Glc3-glucosidase) or mammalian Golgi mannosidase 1 (alpha-1,2-specific) in the glycoprotein processing pathway; the formation of lipid-linked oligosaccharide precursor (dolichol pyrphosphate oligosaccharide) and the transfer of lipid-linked oligosaccharide to proteins. Preparations in ice-cold H2O should be used immediately. The half-time for decomposition of bromoconduritol A (debromination) is 16 min (H2O, pH 7.3, 37oC). Under similar conditions, the half-life of bromoconduritol B is 2 mins. Working concentration for the inhibition of glycoprotein
ReferencesProc. Natl. Acad. Sci. USA, 79, 6787-6791 (1982), Biochimie, 64, 977-1000 (1982), Trends Bio. Sci., 9, 32-34 (1984)
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Bromoconduritol (Mixture of Isomers)
Price(USD)
SizePrice(USD)Discount
5mg$200.0010% OFF
25mg$840.0010% OFF
10mg$380.0010% OFF
50mg$1600.0010% OFF
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