Brazilin

Catalogue number C107922
Chemical nameBrazilin
CAS Number474-07-7
Synonyms(6aS,11bR)-7,11b-dihydro-6H-indeno[2,1-c][1]benzopyran-3,6a,9,10-tetrol
Molecular WeightC16H14O5
Formula286.3
Purity98%
Physical DescriptionRed powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Brazilin acts a novel collagen receptor agonist. Brazilin is a plant-based natural product, may offer therapeutic potential as intended anti-thrombotic agents for targeting of collagen receptors or to be used a useful tool for the study of detailed mechanisms in collagen receptors-mediated platelet activation.


Several studies have shown that the anti-hyperglycemic, anti-hepatotoxic, and anti-inflammatory effects of brazilin are caused by the inhibition of inducible nitric oxide synthase (NOS) in macrophage cells, and vasorelaxation induced by the activation of NOS in endothelial cells.
Brazilin has the effect of inhibiting and inducing apoptosis to human bladder cancer cell T24. It showed significant inhibition to the growth of T24 and could prolong the lifetime of tumor-bearing mice.

References1. Journal of Biomedical Science, 2013, 20, 4.
2. Eur. J. Pharmacol, 2003, 468, 37-45.
3. J. Wood Sci., 2010, 56(1), 77-81.
4. Arch. Pharm. Res., 1998, 21, 140-146.
5. Drug Chem. Toxicol., 1992, 15, 81-91.
6. Planta Med., 2004, 70(8), 740-744.
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Brazilin
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
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