Beta-Amyrin palmitate

Catalogue number C100011
Chemical nameBeta-Amyrin palmitate
CAS Number5973-06-8
SynonymsOlean-12-en-3-ol,hexadecanoate, (3b)-(9CI); Olean-12-en-3b-ol, palmitate (8CI); Palmitic acid, olean-12-en-3b-yl ester (8CI); Balanophorin A; Palmitoyl-b-amyrin; b-Amyrin 3-palmitate; b-Amyrin hexadecanoate; b-Amyrin palmitate; b-Amyryl hexadecanoate
Molecular WeightC46H80O2
Formula665.1
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applicationsbeta-Amyrin palmitate, like mianserin and imipramine, reduced the duration of immobility of mice significantly in a dose-dependent manner (5, 10 and 20 mg kg-1). beta-Amyrin palmitate (5, 10 and 20 mg kg-1) or mianserin (5, 10 and 20 mg kg-1) elicited a dose-related reduction in locomotor activity of mice and antagonized locomotor stimulation induced by methamphetamine. In contrast, imipramine (5, 10 and 20 mg kg-1) increased locomotor activity and potentiated methamphetamine-induced hyperactivity. beta-Amyrin palmitate showed no effect on reserpine-induced hypothermia, whilst mianserin (10 mg kg-1) and imipramine (10 and 20 mg kg-1) antagonized the reserpine-induced effect. beta-amyrin palmitate has similar properties in some respects to mianserin and might possess a sedative action.
beta-Amyrin palmitate might release norepinephrine from newly synthesized pools, and thus, it might activate noradrenergic activity.
References1. Journal of Herbal Pharmacotherapy, 2008, 7(2), 31-47.
2. J Pharm Pharmacol., 1993, 45(6), 545-550.
3. Life Sciences, 1993, 52(3), 289-296.
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Beta-Amyrin palmitate
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