Berberine

Catalogue number C107886
Chemical nameBerberine
CAS Number2086-83-1
SynonymsBerbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI); Umbellatine(6CI);Berbericine;Berberin;Majarine;Thalsine;Umbellatin;5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
Molecular WeightC20H18NO4
Formula336.4
Purity98%
Physical DescriptionYellow powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsBerberine has shown some activity against fungal infections, Candida albicans, yeast, parasites, and bacterial/viral infections. Berberine seems to exert synergistic effects with fluconazole even in drug-resistant C. albicans infections. Some research has been undertaken into possible use against MRSA infection.
Berberine is considered antibiotic.
Berberine is a component of some eye drop formulations. There is some evidence it is useful in the treatment of trachoma, and it has been a standard treatment for leishmaniasis.
Berberine prevents and suppresses proinflammatory cytokines, E-selectin, and genes, and increases adiponectin expression which partly explains its versatile health effects.
References1. Journal of the Chinese Chemical Society, 2004, 51, 443-446.
2. Bull. Korean Chem. Soc., 2002, 23(3), 391-394.
3. Alternative Medicine Reviews, 1997, 2(2), 94-103.
4. FEBS Journal, 277: 37. 2010.
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Berberine
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