Auraptenol

Catalogue number C101177
Chemical nameAuraptenol
CAS Number1221-43-8
Synonyms8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxycoumarin
Molecular WeightC15H16O4
Formula260.3
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAnti-hyperalgesic effect.
Auraptenol dose-dependently reverted the mechanical hyperalgesia in mice within the
dose range of 0.05–0.8 mg/kg. In addition, the anti-hyperalgesic effect of auraptenol was
significantly blocked by a selective serotonin 5-HT1A receptor antagonist WAY100635 (1
mg/kg). Within the dose range studied, auraptenol did not significantly alter the general
locomotor activity in mice. assess the potential of auraptenol as a novel analgesic for the
management of neuropathic pain.
Antifibrotic activity.
References1. Tetrahedron, 1965, 21(1), 89-92.
2. doi:10.1038/srep03377
3. Journal of Natural Medicines, 2011, 65(2), 370-374.
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Auraptenol
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