Catalogue number | C209836 |
Chemical name | Atractyloside Calcium Salt |
CAS Number | N/A |
Synonyms | (2β,15α)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-19-Norkaur-16-en-18-oic Acid Calcium Salt; 19-Norkaur-16-en-18-oic acid deriv. 1H-2,10a-Ethanophenanthrene Calcium Salt |
Molecular Weight | C30H43Ca1.5O16S2 |
Formula | 783.9 |
Purity | 98% |
Physical Description | Pale Yellow Solid |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Atractyloside Calcium Salt is a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. Atractyloside induces the release of ahyaluronidase-induced murine WW domain-containing oxidoreductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity. |
References | Qin, Z.H. et al.: J. Biol. Chem., 276, 8079 (2001); Chang, N.S. et al.: J. Biol. Chem., 276, 3361 (2001); Ziegler, M. et al.: J. Biol. Chem., 268, 25320 (1993); Marzo, I. et al.: Science, 281, 2027 (2027); Vieira, H.L. et al.: Cell Death Differ., 7, 1146 (2000); |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
Size | Price(USD) | Discount |
500µ | $85.00 | 10% OFF |
g | 10% OFF | |
2mg | $270.00 | 10% OFF |
10mg | $995.00 | 10% OFF |
1mg | $150.00 | 10% OFF |
5mg | $595.00 | 10% OFF |
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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