Agomelatine

Catalogue number C200137
Chemical nameAgomelatine
CAS Number138112-76-2
SynonymsN-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide; N-[2-(7-Methoxy-1-naphthyl) ethyl]acetamide; S 20098; Valdoxan;
Molecular WeightC15H17NO2
Formula243.3
Purity98%
Physical DescriptionWhite to Off-White Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAgomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
ReferencesYous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),
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Agomelatine
Price(USD)
SizePrice(USD)Discount
5mg$55.0010% OFF
25mg$225.0010% OFF
100mg$460.0010% OFF
10mg$95.0010% OFF
50mg$305.0010% OFF
1g$950.0010% OFF
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