Aflatoxin B1

Catalogue number C200100
Chemical nameAflatoxin B1
CAS Number1162-65-8
Synonyms(6aR,9aS)-2,3,6a,9a-Tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3’,2’:4,5]furo[2,3-h][1]benzopyran-1,11-dione; (-)-Aflatoxin B1; AFB1; NSC 529592;
Molecular WeightC17H12O6
Formula312.27
Purity98%
Physical DescriptionWhite to Light Yellow Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation. Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR). Aflatoxin B1 is one of the most potent environmental mutagens and carcinogens known.
ReferencesCifford, R., et al.: Nature, 209, 312 (1966), Wogan, et al.: Food Cosmet. Toxicol., 12, 681 (1974), Sinz, M.W., et al.: J. Toxicol. Toxin Rev., 10, 87 (1991),
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Aflatoxin B1
Price(USD)
SizePrice(USD)Discount
1mg$45.0010% OFF
5mg$95.0010% OFF
25mg$450.0010% OFF
2mg$50.0010% OFF
10mg$175.0010% OFF
50mg$900.0010% OFF
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