8-Oxo-Benzylguanine

Catalogue number C250882
Chemical name8-Oxo-Benzylguanine
CAS Number158754-46-2
Synonyms2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043
Molecular WeightC12H11N5O2
Formula257.25
Purity98%
Physical DescriptionTan Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications8-Oxo-Benzylguanine is a derivative of O-Benzylguanine, an reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. O-Benzylguanine is known to assists in the protection against carcinogenic and therapeutic alkylating agents.
ReferencesDolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)
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8-Oxo-Benzylguanine
Price(USD)
SizePrice(USD)Discount
50mg$150.0010% OFF
500mg$1200.0010% OFF
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