3α,7α,12α-Trihydroxycoprostanic Acid

Catalogue number C260771
Chemical name3α,7α,12α-Trihydroxycoprostanic Acid
CAS Number547-98-8
Synonyms(3α,5β,7α,12α)-3,7,12-Trihydroxycholestan-26-oic Acid; 3α,7α,12α-Trihydroxy-5β-cholestan-26-oic Acid; 3α,7α,12α-Trihydroxycoprostanic Acid; 5β-Cholestane-3α,7α,12α-trio
Molecular WeightC27H46O5
Formula450.65
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications3α,7α,12α-Trihydroxycoprostanic Acid is a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α,12α-Trihydroxycoprostanic Acid.
ReferencesHanson, R. F., et al.: Science (Washington, DC, U. S.), 203, 1107 (1979)
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3α,7α,12α-Trihydroxycoprostanic Acid
Price(USD)
SizePrice(USD)Discount
10mg$150.0010% OFF
50mg$675.0010% OFF
25mg$350.0010% OFF
100mg$1225.0010% OFF
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