Catalogue number | C107996 |
Chemical name | 3,4-Dihydroxybenzaldehyde |
CAS Number | 139-85-5 |
Synonyms | Protocatechualdehyde; Protocatechuic aldehyde; Rancinamycin IV; 3,4-Dihydroxybenzyl aldehyde. |
Molecular Weight | C7H6O3 |
Formula | 138.1 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Electrocatalysis of NADH Oxidation with Electropolymerized Films of 3,4-Dihydroxybenzaldehyde. 3,4-dihydroxybenzaldehyde was found to scavenge DPPH radical, hydroxyl radical and intracellular ROS. Also it chelated Fe2+. In in vitro oxidative DNA damage assay and the expression level of phospho-H2A.X, it inhibited oxidative DNA damage and its treatment decreased the expression level of phospho-H2A.X. And in oxidative cell death and apoptosis assay via MTT assay and Hoechst 33342 staining, respectively, the treatment of 3,4-dihydroxybenzaldehyde attenuated H2O2-induced cell death and apoptosis. These results suggest that the barley may exert the inhibitory effect on H2O2-induced tumor development by blocking H2O2-induced oxidative DNA damage, cell death and apoptosis. |
References | 1. Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 955C; 958C; 959A; 959B; 976A. 2. Anal. Chem., 1994, 66(23), 4337-4344. 3. Anal. Chem., 1997, 69(19), 4065-4075. 4. Phytomedicine, 2009, 16(1), 85-94. |
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