3-(4-Maleimidoacetamido)propyl-25-Hydroxy-Vitamin D3

Catalogue number C242072
Chemical name3-(4-Maleimidoacetamido)propyl-25-Hydroxy-Vitamin D3
CAS NumberN/A
Synonyms2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(3-(((S,Z)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)propyl)acetamide
Molecular WeightC36H54N2O5
Formula594.82
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications3-(4-Maleimidoacetamido)propyl-25-Hydroxy-Vitamin D3 is a derivative of Vitamin D3, the vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. It occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. It modulates the proliferation and differentiation of both normal and cancer cells. It also has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells.
ReferencesHaussler, R., et al.: J. Biol. Chem., 247, 2328 (1972); Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003); Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003); Welsh, J., et al.: J. Nutr., 133, 2425S (2003)
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3-(4-Maleimidoacetamido)propyl-25-Hydroxy-Vitamin D3
Price(USD)
SizePrice(USD)Discount
2.5mg$200.0010% OFF
10mg$840.0010% OFF
5mg$440.0010% OFF
25mg$1600.0010% OFF
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