3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088

Catalogue number C202381
Chemical name3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
CAS NumberN/A
Synonyms
Molecular WeightC53H55N5O10S
Formula954.1
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088 is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
ReferencesD’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)
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3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
Price(USD)
SizePrice(USD)Discount
1mg$105.0010% OFF
5mg$475.0010% OFF
2mg$200.0010% OFF
10mg$895.0010% OFF
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