28-O-Methyl-rapamycin

Catalogue number C255287
Chemical name28-O-Methyl-rapamycin
CAS Number159351-88-9
Synonyms23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine Rapamycin Deriv.;
Molecular WeightC52H81NO13
Formula928.2
Purity98%
Physical DescriptionWhite Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
ReferencesMartel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
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28-O-Methyl-rapamycin
Price(USD)
SizePrice(USD)Discount
1mg$150.0010% OFF
10mg$1200.0010% OFF
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