22-Oxa-9,25-dihydroxyvitamin D3

Catalogue number C250725
Chemical name22-Oxa-9,25-dihydroxyvitamin D3
CAS NumberN/A
Synonyms(1S,3aR,7aS,Z)-4-((Z)-2-((S)-5-Hydroxy-2-methylenecyclohexylidene)ethylidene)-1-((S)-1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyloctahydro-1H-inden-5-ol
Molecular WeightC26H42O4
Formula418.61
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications22-Oxa-9,25-dihydroxyvitamin D3 is an analogue of Vitamin D3 (V676045), which mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. Occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
ReferencesHaussler, R., et al.: J. Biol. Chem., 247, 2328 (1972); Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003); Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003); Welsh, J., et al.: J. Nutr., 133, 2425S (2003)
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22-Oxa-9,25-dihydroxyvitamin D3
Price(USD)
SizePrice(USD)Discount
10mg$24750.0010% OFF
25mg$29750.0010% OFF
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