Catalogue number | C243439 |
Chemical name | 2-Methoxy 17β-Estradiol-16,16,17-d3 |
CAS Number | N/A |
Synonyms | (17β)-2-Methoxy-estra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; 2-Hydroxyestradiol-16,16,17-d3 2-Methyl Ether; 2-Methoxyestra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; NSC 659853-d3; |
Molecular Weight | C18H23D3O3 |
Formula | 305.43 |
Purity | 98% |
Physical Description | Crystalline Solid |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | A natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. |
References | Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995), D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1994), Forsis, T., et al.: Nature, 368, 237 (1994) |
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