2,2,2-Trichloroethyl Chloroformate

Catalogue number C260074
Chemical name2,2,2-Trichloroethyl Chloroformate
CAS Number17341-93-4
SynonymsCarbonochloridic Acid 2,2,2-Trichloroethyl Ester; Chloro-formic Acid 2,2,2-Trichloroethyl Ester; 2,2,2-Trichloro-ethanol Chloroformate; (Trichloroethoxy)chloroformate; 2,2,2-Trichloroethoxycarbonyl Chloride; Chloroformic Acid 2,2,2-Trichloroethyl Ester; N
Molecular WeightC3H2Cl4O2
Formula211.86
Purity98%
Physical DescriptionClear Colorless Oil
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
ReferencesMontzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974); Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014); Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)
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2,2,2-Trichloroethyl Chloroformate
Price(USD)
SizePrice(USD)Discount
1g$110.0010% OFF
50 g$190.0010% OFF
10 g$150.0010% OFF
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