17-(Allylamino-d5) Geldanamycin

Catalogue number C200423
Chemical name17-(Allylamino-d5) Geldanamycin
CAS NumberN/A
Synonyms17-Demethoxy-17-(2-propenylamino-d5)geldanamycin; 17-(Allylamino-d5)-17-demethoxygeldanamycin; 17-(Allylamino-d5)-17-desmethylgeldanamycin; 17-Demethoxy-17-(allylamino-d5)geldanamycin; 17AAG-d5; CP 127374-d5; KOS 953-d5; NSC 330507-d5; Tanespimycin-d5;
Molecular WeightC31H38D5N3O8
Formula590.72
Purity98%
Physical DescriptionDark Purple Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPotent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
ReferencesSchnur, R.C., et al.: J. Med. Chem., 38, 3806 (1995), Nimmanapalli, R., et al.: Cancer Res., 61, 1799 (2001), Basso, A.D., et al.: Oncogene, 21, 1159 (2002),
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17-(Allylamino-d5) Geldanamycin
Price(USD)
SizePrice(USD)Discount
1mg$275.0010% OFF
10mg$2200.0010% OFF
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