1-(3-Methoxypropyl)-4-piperidinamine

Catalogue number C242838
Chemical name1-(3-Methoxypropyl)-4-piperidinamine
CAS Number179474-79-4
Synonyms1-(3-Methoxypropyl)piperidin-4-amine; Prucalopride Intermediate
Molecular WeightC8H20N2O
Formula172.27
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
ReferencesShah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009); Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); Yuan, Y., et al.: Zhongguo Yiyao Gongye Zazhi, 43, 5 (2012)
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1-(3-Methoxypropyl)-4-piperidinamine
Price(USD)
SizePrice(USD)Discount
100mg$75.0010% OFF
1g$275.0010% OFF
5g$675.0010% OFF
250mg$110.0010% OFF
2.5g$450.0010% OFF
10g$1195.0010% OFF
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