(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester

Catalogue number C250821
Chemical name(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester
CAS Number89886-73-7
Synonyms(2S-trans)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester; (2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carboxylic Acid; (2S,3S)-2,3-Oxiranedicarboxylic Acid 2-Ethyl Ester
Molecular WeightC6H8O5
Formula160.12
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.
ReferencesLee, J. et al.: Bioorg. Med. Chem. Lett., 22, 1340 (2012); Carmi, C. et al.: J. Med. Chem., 53, 2038 (2010); Hillaert, U. et al.: Angew. Chem. Int. Ed., 48, 1629 (2009);
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(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester
Price(USD)
SizePrice(USD)Discount
250mg$140.0010% OFF
2.5g$1120.0010% OFF
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