(-)-α-Kainic Acid

Catalogue number C240619
Chemical name(-)-α-Kainic Acid
CAS Number487-79-6
Synonyms(2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-Kainic Acid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; Kainic Acid; L-α-Kain
Molecular WeightC10H15NO4
Formula213.23
Purity98%
Physical DescriptionWhite to Off-White Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications(-)-α-Kainic Acid is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.
ReferencesWacker, D.A., et al.: Synlett, 503 (1997), Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)’
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(-)-α-Kainic Acid
Price(USD)
SizePrice(USD)Discount
25mg$235.0010% OFF
200mg$1450.0010% OFF
100mg$775.0010% OFF
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