Catalogue number | C108575 |
Chemical name | Polydatin |
CAS Number | 27208-80-6 |
Synonyms | (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
Molecular Weight | C20H22O8 |
Formula | 390.4 |
Purity | 98% |
Physical Description | White cryst. |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Polydatin has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell studies report that Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels. Polydatin preconditioning (PPC) has been reported to be protective against brain and intestine ischemia/reperfusion injury. It also exerts cardioprotective effect by the activation of PKC-K(ATP)-dependent signaling and the direct anti-oxidative stress mechanisms. Polydatin affects lipopolysaccharide‘s induction on VEC ICAM-1;Polydatin affects the neutrophils’s chemotaxis reaction inspired by lipopolysaccharide; Polydatin affects smooth muscle and Cardiomyocytes PKC under the situation of ischemia, hypoxia, burn serum, and LPS; Polydatin was used in treating severe Acute Pancreatitis in the early stage; Polydatin affects TLR4 when reducing the injury occurred during perfusing blood to ischemic Rabbit lung; Experiments and researches both in vitro and in vivo on of Polydatin curing Viral Myocarditis. |
References | 1. Separation and Purification Technology, 2009, 66(2), 329-339. 2. Phytomedicine, 2012, 19(8-9), 677-681. 3. Planta Med., 2004, 70(12), 1128-1134. 4. Phytomedicine, 2011, 19(1), 8-12. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
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10mg | Inquiry | N/A |
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Sent to your order to our email: info@coompo.com
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