N,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate

Catalogue number C263013
Chemical nameN,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate
CAS Number212333-72-7
SynonymsN-[(Dimethylamino)[(1-oxido-2-pyridinyl)thio]methylene]-N-methylmethanaminium Hexafluorophosphate(1-); HOTT; S-(1-Oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium Hexafluorophosphate;
Molecular WeightC10H16F6N3POS
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsN,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is a reagent used in the preparation of hindered Barton esters from hindered carboxylic acid precursors. N,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is also used as a coupling reagents for peptide bond formations and amidation reactions.
ReferencesGarner, P. et al.: J. Org. Chem., 63, 5732 (1998); Bailen, M.A. et al.: J. Org, Chem., 64, 8936 (1999);
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N,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate
5g$125.0010% OFF
25g$500.0010% OFF
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