Lyoniside

Catalogue number C101520
Chemical nameLyoniside
CAS Number34425-25-7
Synonyms(+)-Lyoniside;[[(1S)-1α-(3,5-Dimethoxy-4-hydroxyphenyl)-3α-(hydroxymethyl)-6,8-dimethoxy-7-hydroxytetralin-2β-yl]methyl]β-D-xylopyranoside
Molecular WeightC27H36O12
Formula552.6
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsIn vitro, the purified lyoniside was evaluated for antioxidant, allelopathic and antifungal activities. It showed significant radical scavenging properties in a 2,2-diphenyl-1- picrylhydrazyl (DPPH) assay with IC50 of 23 μg ml−1. Applied at concentration of 10 μg ml−1, it suppressed by 75% the seedling radical growth of Lactuca sativa and Lepidium sativum, and exerted strong inhibitory effect (55%) on germination of Larix decidua. Moreover, the synergistic action of lyoniside and triterpene acids was demonstrated in inhibitory effect exerted on germination and growth of Pinus sylvestris. Among 5 tested fungi strains of Ascomycota, the highest susceptibility was shown by Fusarium oxysporum and Mucor hiemalis, with mycelial growth inhibited by lyoniside concentration of 50 μg ml−1 by 78 and 80%, respectively.
Triterpenic acids and lyoniside exerted slightly inhibitory effect on germination (reduction by 27 and 10%, respectively) and growth of seedlings (radicles by approx. 20%, shoots by 50 and 25%). However, the most dramatic effect was exerted by their mixture, which inhibited the germination by 80% and suppressed the growth by approx. 70%. These results point to the synergism of the activity of more polar lyoniside with less polar triterpene acids in V. myrtillus allelopathic potential.
References1. Archives of Pharmacal Research, 2011, 34(9), 1443-1450.
2. Archives of Pharmacal Research, 2012, 35(1), 87-92.
3. Phytochemistry Letters, 2011, 4(2), 138-143.
4. Phytochemistry, 1992, 31(10), 3654-3656.
5. Planta Med., 2008, 74, 163.
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Lyoniside
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