Catalogue number | C101520 |
Chemical name | Lyoniside |
CAS Number | 34425-25-7 |
Synonyms | (+)-Lyoniside;[[(1S)-1α-(3,5-Dimethoxy-4-hydroxyphenyl)-3α-(hydroxymethyl)-6,8-dimethoxy-7-hydroxytetralin-2β-yl]methyl]β-D-xylopyranoside |
Molecular Weight | C27H36O12 |
Formula | 552.6 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | In vitro, the purified lyoniside was evaluated for antioxidant, allelopathic and antifungal activities. It showed significant radical scavenging properties in a 2,2-diphenyl-1- picrylhydrazyl (DPPH) assay with IC50 of 23 μg ml−1. Applied at concentration of 10 μg ml−1, it suppressed by 75% the seedling radical growth of Lactuca sativa and Lepidium sativum, and exerted strong inhibitory effect (55%) on germination of Larix decidua. Moreover, the synergistic action of lyoniside and triterpene acids was demonstrated in inhibitory effect exerted on germination and growth of Pinus sylvestris. Among 5 tested fungi strains of Ascomycota, the highest susceptibility was shown by Fusarium oxysporum and Mucor hiemalis, with mycelial growth inhibited by lyoniside concentration of 50 μg ml−1 by 78 and 80%, respectively. Triterpenic acids and lyoniside exerted slightly inhibitory effect on germination (reduction by 27 and 10%, respectively) and growth of seedlings (radicles by approx. 20%, shoots by 50 and 25%). However, the most dramatic effect was exerted by their mixture, which inhibited the germination by 80% and suppressed the growth by approx. 70%. These results point to the synergism of the activity of more polar lyoniside with less polar triterpene acids in V. myrtillus allelopathic potential. |
References | 1. Archives of Pharmacal Research, 2011, 34(9), 1443-1450. 2. Archives of Pharmacal Research, 2012, 35(1), 87-92. 3. Phytochemistry Letters, 2011, 4(2), 138-143. 4. Phytochemistry, 1992, 31(10), 3654-3656. 5. Planta Med., 2008, 74, 163. |
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After Receiving
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