Kaempferol

Catalogue number C107954
Chemical nameKaempferol
CAS Number520-18-3
Synonyms3,5,7-trihydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one
Molecular WeightC15H10O6
Formula286.2
Purity98%
Physical DescriptionYellow powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Kaempferol have a wide range of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective, neuroprotective, antidiabetic, antiosteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic, and antiallergic activities.
Keampferol is a strong antioxidant and helps to prevent oxidative damage of our cells, lipids and DNA. Kaempferol seems to prevent arteriosclerosis by inhibiting the oxidation of low density lipoprotein and the formation of platelets in the blood. Studies have also confirmed that kaempferol acts as a chemopreventive agent, which means that it inhibits the formation of cancer cells.


Kaempferol inhibits monocyte chemoattractant protein (MCP-1). MCP-1 plays a role in the initial steps of atherosclerotic plaque formation. Kaempferol can help to fight cancer because it reduces the resistance of cancer cells to anti-cancer drugs such as vinbalstine and paclitaxel.


Kaempferol consumption is also correlated with a reduced lung cancer incidence. Kaempferol may be a potent prophylactic against NOX-mediated neurodegeneration.

References1. J. Shenyang Pharm. Univ., 2000, 17(4), 267-268.
2. J. Nat. Prod., 1991, 54(5), 1427-1429.
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Kaempferol
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