Cyanidin-3-O-arabinoside chloride

Catalogue number C104044
Chemical nameCyanidin-3-O-arabinoside chloride
CAS Number111613-04-8
Molecular WeightC20H19ClO10
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze

Antioxidant activity.

Peroxynitrite caused DNA strand breakage (63 ± 1.9% single strand vs 3 ± 0.9% single strand in control cells), as measured by the alkaline unwinding assay, and caused an activation of PARS, as measured by the incorporation of radiolabeled NAD+ to nuclear proteins. cyanidin-3-O-glucoside (as chloride) (0.085 μM; 0.028 μM; 0.0085 μM) reduced the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage and PARS activation in HUVECs. Vascular rings exposed to peroxynitrite exhibited reduced endothelium-dependent relaxant responses in response to acetylcholine as well as a vascular contractility dysfunction in response to norepinephrine. The development of this peroxynitrite-induced vascular dysfunction was ameliorated by the blackberry juice (different dilutions that contained 80 ppm;40 ppm;14.5 ppm of cyanidin-3-O-glucoside) and cyanidin-3-O-glucoside (as chloride) (0.085 μM;0.028 μM;0.0085 μM)

References1. Journal of Chromatography A, 1983, 279, 365-372.
2. Journal of Food Science, 1988, 53(4), 1241-1242.
3. Life Sciences, 2003, 73(9), 1097-1114.
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