Catalogue number | C107934 |
Chemical name | Aloeemodin |
CAS Number | 481-72-1 |
Synonyms | 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione |
Molecular Weight | C15H10O5 |
Formula | 270.2 |
Purity | 98% |
Physical Description | Pale yellow powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Aloe emodin has a strong stimulant-laxative action. Aloe emodin is not carcinogenic when applied to the skin, althougth it may increase the carcinogenicity of some kind of radiation. Aloe-emodin (AE) has a specific in vitro and in vivo antineuroectodermal tumor activity. The growth of human neuroectodermal tumors is inhibited in mice with severe combined immunodeficiency without any appreciable toxic effects on the animals. The compound does not inhibit the proliferation of normal fibroblasts nor that of hemopoietic progenitor cells. The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energy-dependent pathway of drug incorporation. Taking into account its unique cytotoxicity profile and mode of action, AE might represent a conceptually new lead antitumor drug. Aloe-emodin appears to have some protective effect not only against hepatocyte death but also on the inflammatory response subsequent to lipid peroxidation. |
References | 1. J. Org. Chem., 1980, 45(1), 24-28. 2. Magnetic Resonance in Chemistry, 1992, 30(4), 359-360. 3. Phytochemistry., 1989, 28(12), 3553-3555. 4. Cancer Res., 2004, 64(1), 108-116. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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To place an order, please provide the following information.
1) Your name and telephone number
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3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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