1,3-Dicaffeoylquinic acid

Catalogue number C108539
Chemical name1,3-Dicaffeoylquinic acid
CAS Number30964-13-7
Synonyms(1R,3R,4S,5R)-1,3-bis[(E)-3-(3,4-dihydroxyphenyl)-1-oxoprop-2-enoxy]-4,5-dihydroxy-1-cyclohexanecarboxylic acid
Molecular WeightC25H24O12
Physical DescriptionWhite powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze

1,5-Dicaffeoylquinic acid has antioxidant signaling properties that upregulate GSH synthesis by stimulating the Nrf2 pathway in astrocytes and protects them from cell death in an in vitro model of ischemia/reperfusion.

1,5-dicaffeoylquinic acid was found to have neuroprotective effects. 1,5-dicaffeoylquinic acid prevents Aβ42-induced neurotoxicity through the activation of PI3K/Akt followed by the stimulation of Trk A,then the inhibition of GSK3β as well as the modulation of Bcl-2/Bax.

References1. Journal of Mass Spectrometry, 2004, 39(4), 384-395.
2. Planta Med., 2005, 71(9), 871-876.
3. Tetrahedron Letters, 2001, 42(19), 3383-3385.
4. Chem. Pharm. Bull., 2001, 49(7), 915-917.
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1,3-Dicaffeoylquinic acid
20mg$182.005% OFF
50mg$419.008% OFF
100mg$712.0015% OFF
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